1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility.

2. Uses high-quality nutraceuticals in an effective evidence-based and efficaciously dosed formula.

Oat Seed

• May support antioxidant function and cardiovascular health (185).

Alfalfa Leaf

• Supports immune, digestive, and energy levels.
• The high antioxidant capacity allows for free radical scavenging of reactive oxygen species.

Psyllium Husk

• Supports healthy digestion, gut microbiome, healthy bowel movements, blood sugar regulation, and natural appetite suppressant (269).
• Increases stool water significant changes in the microbiota in constipated patients (269).
• Reduces constipation via reduction of the bacterial genus associated with hard stools (Christensenella) (269).

 Lactobacillus Acidophilus 

• Supports athletic performance, enhanced gut microbiome, increased muscle mass, immune health, reduced cortisol levels, digestive health, cognitive function, and improved allergy symptoms (103,104, 107, 108, 109).
• Supports 70% of a gut-immunological axis (gut immune system) via enhanced mucosal immune response (toll-like receptors), and upregulation of genetic markers associated with macrophage (gut-immune cell) activity (108, 109).
• Supports digestive and immune health via decreased irritable bowl symptoms, suppression of helicobacter pylori growth (pathogenic bacteria), reduced histamine (reduced allergic response), and reduced gut inflammation (103,104, 107, 108, 109).
• Supports athletic performance via reduction of respiratory tract infections, reduced muscle damage, improved body composition, reduction lactate induced exercise (muscle burn), and body composition (108).
• Supports gut-brain axis via increased neural, endocrine (hormonal), and anti-inflammatory modulation of the hypothalamic-pituitary-adrenal (HPA) axis (108).
• Reduces inflammation via activation of Toll-like receptors (TLRs) and downregulates the expression of nuclear factor (NF)-κB and pro-inflammatory cytokines (inflammation markers) (109).

Rhubarb Root

• Supports immune health, antioxidant function, reduces inflammation, and may combat carcinogenesis (277,278).
• Combats carcinogenesis via inhibition of angiogenesis (blood vessel formation of tumors) (278).
• Reduces inflammation via reduction of inflammatory cytokines, increased reactive oxygen species scavenging ability (277,278).

Gentian Root

• Supports immune and cardiovascular health, and anti-inflammatory support (279).
• Supports cardiovascular health via reduced anti-atherosclerotic activities (279).
• Combats atherosclerosis by reducing endothelial inflammation, and smooth muscle cell inflammation (279).

Aloe Vera Leaf

• Supports digestive, cardiovascular, and metabolic health (270).
• Supports reduction in total and low-density lipoprotein cholesterol (LDL-C) levels, glucose, and H1AC (270).
• Supports cardiovascular health via reduced the levels of fasting blood glucose, HbA1c, triglycerides, total cholesterol, LDL cholesterol, and increased HDL cholesterol (271).
• Increases glucose absorption via high molecular weight enhancing glucose transport (271).
• Reduces serum concentrations of cholesterol via reducing absorption of cholesterol from the gut (271).

Cascara Sagrada

• Supports digestive health and regular bowel movements.

Goldenseal root

• Supports digestive health, antibacterial activity, and antioxidant support (201, 202). 
• Supports antioxidant function via levels of berberine (alkaloid) (201,202).

Buckthorn bark

• Supports healthy detoxification, healthy bowel movements, and digestive support (280).

Bentonite

• May support healthy detoxification.*

CAUTION: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.