1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility.

2. Uses high-quality nutraceuticals in an effective evidence-based and efficaciously dosed formula.

Magnesium 

• Supports optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91).
• Supports biological reactions such as ATP-fueled reactions and pancreatic insulin secretion (90,91).
• Supports reduction systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91).
• Reduces peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91).

Zinc

• Supports immune function, skin health, cognitive function, and vision (172,173).
• Supports stimulation of the innate and adaptive immune system (172,173).
• Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173).
• Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173).

Tribulus Terrestris

• Supports sexual function, increased testosterone, cardiovascular health, supports healthy urinary tract function, supports athletic performance, and aids as a neuroprotective agent (137,138).
• Supports sexual health, via activating aphrodisiacs, increased spermatogenesis, sperm motility, increased free testosterone, and increase of androgenic (hormone) action via the activation of endogenous testosterone production (137,138).
• Supports cardiovascular health via decreased arterial inflammation levels of tumor necrosis factor (TNF)-α and interleukin (IL)-6 (137,138).
•  Supports neuroprotective properties via protection of neuron injury, and cerebral ischemia–reperfusion by suppressing brain inflammatory markers (NF-κB, TNF-α and IL-1β) (137,138).

Chrysin

• Supports immune health, cardiovascular health, and increased testosterone (209).
• Supports immune health via suppression of pro-oxidant enzymes, scavenging free radicals, and reduced inflammatory cytokines (markers of inflammation) (209). 
• Supports cardiovascular health via increased bioavailability of endothelial nitric oxide, reduced prevalence of atherosclerosis, reduced thrombogenesis (blood clotting) and reduced vascular (blood vessel) inflammation (209).
• Supports increased testosterone via blocking of androgens into estrogen (210). 

Horny Goat Weed

• Supports increased sexual drive, increased testosterone, reduced progression of atherosclerosis, increased nitric oxide levels, and reduced arterial (blood vessel) inflammation levels (126,127).
• Reduces arterial inflammation via reduction of free-radical-induced peroxidation in erythrocytes, and increased nitric oxide levels (126,127).
• Supports arterial health (health of blood vessels) via attenuating DNA damage, correcting endothelial dysfunction (126,127).
• Represses macrophage-derived foam cell formation, inhibiting platelet activation, and reduces oxLDL-induced monocyte adhesion to endothelial cells (126,127).

Longjack (Tongkat Ali)

• Reduces stress hormones (cortisol), increases free testosterone, enhances mood, and supports sexual function (132).

Saw Palmetto

• Supports prostate health, cardiovascular health, and increased hair growth (133,134).
• Supports prostate health via anti-androgenic and anti-inflammatory effects resulting in reduced Benign prostatic hyperplasia (134).

Hawthorn Berries

• Supports cardiovascular health and combats metabolic syndrome (165).
• Supports cardiovascular health via reduced atherosclerotic lesion areas, reduced cholesterol synthesis (acyl-coA-cholesterol acyltransferase enzyme), reduced very-low-density lipoproteins (VLDL), and inhibited platelet aggregation (165).

Cissus Quadrangularis

• Supports joint health, antioxidant function, cardiovascular health, and reduced body fat (211, 212).
• Supports antioxidant function via increased free radical scavenging capacity and reduced inflammatory cytokines (211, 212).
• Supports Cardiovascular health via decreases in the waist and hip circumferences, reduced blood pressure, total cholesterol, triglycerides, fasting blood glucose, and leptin levels (211, 212).
• Reduces body fat via decreased Enzymatic activity of pancreatic lipase and decreased activity of genetic modulators of adipogenesis (fat cell growth) such as C/EBPα, PPARγ, SREBP-1c (genetic regulators of fat cell growth) (211, 212).
• Supports joint health via reduced inflammation in connective tissue (211, 212).

• 90. Boyle, N. B., Lawton, C., & Dye, L. (2017). The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients, 9(5), 429. https://doi.org/10.3390/nu9050429
• 91. Verma, H., & Garg, R. (2017). Effect of magnesium supplementation on type 2 diabetes associated cardiovascular risk factors: a systematic review and meta-analysis. Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 30(5), 621–633. https://doi.org/10.1111/jhn.12454
• 126. Kuchakulla, M., Narasimman, M., Soni, Y., Leong, J. Y., Patel, P., & Ramasamy, R. (2021). A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. International journal of impotence research, 33(3), 311–317. https://doi.org/10.1038/s41443-020-0285-x
• 127. Fang, J., & Zhang, Y. (2017). Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed. Frontiers in pharmacology, 8, 734. https://doi.org/10.3389/fphar.2017.00734
• 132. Rehman, S. U., Choe, K., & Yoo, H. H. (2016). Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology. Molecules (Basel, Switzerland), 21(3), 331. https://doi.org/10.3390/molecules21030331
• 165. Dehghani, S., Mehri, S., & Hosseinzadeh, H. (2019). The effects of Crataegus pinnatifida (Chinese hawthorn) on metabolic syndrome: A review. Iranian journal of basic medical sciences, 22(5), 460–468. https://doi.org/10.22038/IJBMS.2019.31964.7678
• 172. Maywald, M., Wessels, I., & Rink, L. (2017). Zinc Signals and Immunity. International journal of molecular sciences, 18(10), 2222. https://doi.org/10.3390/ijms18102222
• 173. Wessels, I., Rolles, B., & Rink, L. (2020). The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis. Frontiers in immunology, 11, 1712. https://doi.org/10.3389/fimmu.2020.01712
• 209.  Farkhondeh T, Samarghandian S, Bafandeh F. The Cardiovascular Protective Effects of Chrysin: A Narrative Review on Experimental Researches. Cardiovasc Hematol Agents Med Chem. 2019;17(1):17-27. doi: 10.2174/1871525717666190114145137. PMID: 30648526; PMCID: PMC6865076.
• 210. Gambelunghe C, Rossi R, Sommavilla M, Ferranti C, Rossi R, Ciculi C, Gizzi S, Micheletti A, Rufini S. Effects of chrysin on urinary testosterone levels in human males. J Med Food. 2003 Winter;6(4):387-90. doi: 10.1089/109662003772519967. PMID: 14977449.
• 211. Nash R, Azantsa B, Kuate D, Singh H, Oben J. The Use of a Stem and Leaf Aqueous Extract of Cissus quadrangularis (CQR-300) to Reduce Body Fat and Other Components of Metabolic Syndrome in Overweight Participants. J Altern Complement Med. 2019 Jan;25(1):98-106. doi: 10.1089/acm.2018.0016. Epub 2018 Nov 12. PMID: 29912570; PMCID: PMC6352552.
• 212. Bloomer RJ, Farney TM, McCarthy CG, Lee SR. Cissus quadrangularis reduces joint pain in exercise-trained men: a pilot study. Phys Sportsmed. 2013 Sep;41(3):29-35. doi: 10.3810/psm.2013.09.2021. PMID: 24113700.

CAUTION: Consult with a physician prior to use if you have any medical conditions. Do not use if pregnant or lactating.